“Movement Measurements at Home for Multiple Sclerosis: Walking Speed and Cane Usage Measured by an Ambient Measurement System”. Scientific electronic poster (e-poster) presented at the American Academy of Neurology (AAN) annual conference on April 18, 2016. Authors: Victoria M. J. Smith (MGH / Harvard), Jonathan S. Varsanik (Atlas5D), Kevin R. Patel (MGH / Harvard), Wendy Gabel (Biogen), Glenn Phillips (Biogen), Zebadiah Kimmel (Atlas5D), Eric Klawiter (MGH / Harvard). Video contents copyright 2016 by Atlas5D; all rights reserved.
This study’s objective was to develop continuous in-home outcome measurements to assess gait in adults with multiple sclerosis (MS). Movement measurements were collected continuously for 4 months from the homes of six female people with MS (mean age 56.2, median EDSS 3.5, EDSS range 2-6.5). After two months, sensors were moved to a new location in the home. Spearman correlation was used to correlate in-home continuous gait outcomes with standard clinic gait outcomes. Wilcoxon signed-rank test was used to compare gait outcome for location and time of day. Measured in-home average walking speeds of users demonstrated a moderately strong correlation with Timed 25-Foot Walk (ρ=-0.60, p=0.21). Home cane usage was detected with cane users twice as frequently as non-cane users in a cane-detection measurement. New non-wearable technology provides reliable and continuous in-home assessment of walking speed and cane usage. This study demonstrates feasibility for development of new continuous outcome measures to assess gait in MS and other neurological diseases.